Research

We perform mechanistic studies of enzymes at molecular and atomistic levels to improve our understanding of antibiotic resistance in bacteria and human cancers, in order to inform drug discovery and design.

Deciphering enzyme specificity towards sulfated glycans
Rational design of enzymatic activities facilitated by structural and computational biology.
Activity-based inhibitor design and discovery
Mechanistic enzymology

Our research is funded by

University of Manchester
Wellcome Trust
The Royal Society
The Academy of Medical Sciences
University of Manchester Studentship
Cardiff University Studentship
EPSRC Studentship
Chinese Scholarship Council Studentships x2
University of Manchester-University of Melbourne Studentship