top of page


We perform mechanistic studies of enzymes at molecular and atomistic levels to improve our understanding of antibiotic resistance in bacteria and human cancers, in order to inform drug discovery and design.

  • Deciphering enzyme specificity towards sulfated glycans

  • Rational design of enzymatic activities facilitated by structural and computational biology.

  • Activity-based inhibitor design and discovery

  • Mechanistic enzymology

Our research is funded by

  • University of Manchester

  • Wellcome Trust

  • The Royal Society

  • The Academy of Medical Sciences

  • University of Manchester Studentship

  • Cardiff University Studentship

  • EPSRC Studentship

  • Chinese Scholarship Council Studentships x2

  • University of Manchester-University of Melbourne Studentship

bottom of page