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Contact

 

0.31C (South Wing)

School of Chemistry

Main Building

Cardiff University

Park Place

Cardiff

CF10 3AT

email: jiny6@cardiff.ac.uk

Tel: +44(0)2920870749

Biography

Yi Jin (金轶)took her BSc degree in Chemistry in 2005 from Xiamen University, China. In 2008, she obtained her MSc degree in Organic Chemistry after completing her Master's thesis in the group of Prof. Yufen Zhao (赵玉芬), Academician of CAS, at Xiamen University, working on the synthesis of transition state analogue inhibitors of phosphoserine phosphatase and phosphopeptides. In 2008, she was awarded the prestigious Overseas Research Studentship (ORS) by British Council and came to the UK for her PhD under the guidance of Prof. Jon P. Waltho and Prof. G. Mike Blackburn at the University of Sheffield, UK. During this period, she expanded the usage of metal fluoride complexes as mimics of phosphoryl group in various key enzymes in cellular signal transduction in NMR and crystallography. She stayed in the same lab as a postdoc for 2 years working on the strain catalysis of DNA repairing enzyme UNG using multi-dimensional NMR. In 2014, she moved to the group of Prof. Gideon J. Davies, FRS, FMedSci in YSBL, University of York, UK, working on various carbohydrate processing enzymes, including the first glycosyl hydrolases in sulfo-glycolytic pathways,  the first mannosidase in GH134 family, and using activity based-probes to trap glucuronidases in action. In May 2017, she was appointed as a University Research Fellow at Cardiff University to begin her independent research career. And in November 2019, she was awarded a Wellcome Trust Sir Henry Dale Fellowship for 5 years. 

 

Her research interests involve mechanistic studies and protein interactions of disease-relevant phosphoryl transfer enzymes and carbohydrate processing enzymes using organic synthesis, chemical biology, molecular biology, NMR, and crystallographic approaches. 

Invited talks

2019 Sept   Beijing Normal University. Beijing, China. 

2019 Jun     Max-Planck Developmental Biology. Tubingen, Germany. 

 

2019 May    Pharmaceutical Sciences, Cardiff University. Cardiff, UK.

 

2018 May    European Symposium on Biological and Organic Chemistry. Gregynog, UK.

2018 Jan     Global Scientist Forum. Shenzhen, China.

 

2017 Sept    Xiamen- Cardiff Bilateral Workshop in Chemistry. Xiamen, China.

 

2017 Sept    RSC Chemical Biology and Bioorganic Group Symposium.  Firbush, UK.

2017 Jul       South West Structure Biology Conference. Cardiff, UK. 

 

2017 May     Cardiff Chemistry Conference, Cardiff University. Cardiff, UK. 

 

2017 Jan      Department of Chemical Biology, Xiamen University. Xiamen, China.  

 

2016 Dec     Silk Road Young Scholar’s Forum. Xi’an, China. 

 

2016 Oct      International Conference on Phosphorus Chemistry. Kazan, Russia. 

 

2014 Oct      Krebs Institute Symposium. Sheffield, UK.

 

2010 Oct      White Rose Protein Forum Meeting. Sheffield, UK. 

 

2010 June    Trends in Enzymology. Ascona, Switzerland. 

Cardiff University

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© 2017 by Yi Jin.